Propiverine Hydrochloride Tablets

Propiverine Hydrochloride Tablets are antispasmodic drugs. They are indicated for the treatment of overactive bladder syndrome (OAB) accompanied by symptoms such as urge urinary incontinence, urinary urgency, and frequent urination.

[Specification] 10mg

[Usage and Dosage] Oral administration. Adults: Generally take 20mg (2 tablets) once a day after meals. The maximum daily dosage should not exceed 40mg (4 tablets).

[Packaging] Medicinal PVC hard sheet, PTP aluminum foil blister packaging, 10 sheets per board, 1 board per box.

[Validity Period] Temporarily set at 24 months.

General Information

Drug Name: Generic name is Propiverine Hydrochloride Tablets. The trade name is Hershu.

Main Ingredient: Propiverine hydrochloride, which belongs to the class of anticholinergic drugs.

Pharmacological Action

Propiverine hydrochloride has anticholinergic and antispasmodic effects. It acts by competitively blocking the muscarinic receptors in the smooth muscles of the urinary bladder, thereby reducing the involuntary contractions of the bladder detrusor muscle. This helps to increase the bladder's capacity and decrease the frequency of urination and urgency.

Indications

It is mainly used for the treatment of overactive bladder syndrome. Symptoms that can be alleviated include urinary frequency, urgency, and urge incontinence. It helps patients with overactive bladder to better control their urination and improve their quality of life.

Dosage and Administration

The usual recommended dosage is [specific dosage] taken orally [number of times] a day. The dosage may be adjusted according to the patient's age, symptoms, and response to treatment. It is usually taken with water, and it is advisable to take it at regular intervals. In some cases, the doctor may start with a lower dose and gradually increase it to achieve the optimal therapeutic effect while minimizing side effects.

Adverse Reactions

Anticholinergic Side Effects: Dry mouth is a common side effect, which may be accompanied by a decrease in salivary secretion, leading to difficulties in swallowing and speaking. Blurred vision can also occur due to the relaxation of the ciliary muscle, affecting the ability to focus. Constipation may be experienced as a result of reduced gastrointestinal motility.

Cardiovascular Effects: In some patients, it may cause an increase in heart rate. This is because of the anticholinergic action on the cardiac muscarinic receptors, which can lead to a relative increase in sympathetic tone.

Central Nervous System Effects: Dizziness and drowsiness may be reported. These effects can affect a patient's daily activities and require caution when operating machinery or driving. In rare cases, headache and nervousness may also occur.

Contraindications

Hypersensitivity to propiverine hydrochloride or any of the excipients in the tablets.

Patients with narrow - angle glaucoma, as the anticholinergic effect may increase intraocular pressure and exacerbate the condition.

Severe urinary retention, as the drug may further reduce bladder contractility and worsen the retention.

Gastrointestinal obstruction or paralytic ileus, because the drug can decrease gastrointestinal motility and may aggravate the obstruction.

Precautions

Use in Special Populations: Elderly patients may be more sensitive to the anticholinergic effects of the drug, so close monitoring is required. In pregnant and lactating women, the use of this drug should be carefully considered. It should only be used if the potential benefit outweighs the potential risk to the fetus or infant.

Concomitant Medications: Inform the doctor about all the medications being taken, as propiverine hydrochloride may interact with other drugs. For example, it may interact with other anticholinergic drugs, leading to an increased risk of side effects. It may also interact with some drugs that affect the central nervous system or cardiovascular system.

Monitoring and Follow - up: Regular follow - up appointments are necessary to monitor the efficacy and side effects of the drug. The doctor may adjust the dosage or discontinue the drug based on the patient's condition. If any unusual symptoms or side effects occur, the patient should contact the doctor immediately.