Introduction
Diflucortolone valerate is a corticosteroid used in the treatment of various skin conditions.It can inhibit skin inflammation and allergic reactions, suitable for contact dermatities, eczema vulgaris, neurodermatitis and other local treatment.
Specifications
In house
Chemical Name
17 - (Valeryloxy) - 11β - hydroxy - 6α,9 - difluoro - 16β - methylpregna - 1,4 - diene - 3,20 - dione.
Molecular formula
C27H36F2O5
CAS NO.
59198-70-8
Packing
1kg/tin
Category
Corticosteroid.
Storage
Store in a dark place and keep it sealed.
Indication
Skin Inflammatory Disorders
It is mainly used for treating eczema, psoriasis, seborrheic dermatitis, and contact dermatitis. It can effectively relieve skin symptoms such as itching, scaling, and inflammation.
Allergic Skin Reactions
It is helpful in treating allergic skin conditions like urticaria and allergic contact dermatitis, reducing allergic symptoms such as rashes and itching.
Pharmacological Actions
Anti - Inflammatory
It inhibits the release of inflammatory mediators like prostaglandins and leukotrienes, reducing inflammation - related symptoms such as redness, swelling, and pain. For instance, in dermatitis, it helps alleviate skin inflammation.
Immunosuppressive
It suppresses the immune system by modulating the activity of immune cells like lymphocytes, which is beneficial in treating autoimmune skin diseases.
Anti - Pruritic
It has an antipruritic effect, relieving itching by reducing the skin's inflammatory response and suppressing the release of itch - inducing substances.
Dosage and Administration
It is typically available as a cream, ointment, or lotion for topical use. The usual dosage is to apply a thin layer of the medication evenly to the affected skin area 1 - 2 times daily. The treatment duration varies depending on the type and severity of the skin condition. For acute conditions, it may be used for a short period (about 1 - 2 weeks), while for chronic conditions, long - term use under medical supervision may be necessary, with regular evaluations to adjust the treatment plan as needed.
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